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Even though these effects were observed on mice, all mammals have neurological and cellular similarities, and the team in charge of this study concluded that: “With respect to the treatment of ALS, from both a disease modifying and symptom management viewpoint, clinicaltrials with cannabis are the next logical step.
Recent studies on the effectiveness of cannabidiol in the rare seizure disorders Dravet Syndrome and Lennox-Gastaut syndrome have prompted a biopharmaceutical company to perform clinicaltrials of its own to bring a cannabidiol based drug to the American market through the process of FDA approval. Fig 1: Sucralose (In Study).
Based on the limited existing evidence, the best cannabis strain for migraines may be a Type II that includes both THC and CBD, and a terpene profile that includes beta-caryophyllene, myrcene, linalool, limonene, bisabolol, humulene or pinene. The study called out pinene, myrcene, and beta-caryophyllene as specifically useful terpenes.
Research into the plant’s chemical compounds has also revealed a rich array of terpenes and flavonoids that may also account for the plant’s therapeutic effects (Kotsirilos and McGregor 2021 ). It is unclear whether doctors are feeling completely reassured by laboratory and clinicaltrial research into medicinal cannabis.
Wakshlag is well-known in the veterinary medicine community as the first doctor to conduct an efficacy study in dogs in a clinicaltrial at Cornell using ElleVet CBD/CBDA on dogs with multi-joint discomfort. The clinicaltrial results confirmed more than 80% of dogs showed significant or dramatic improvement.
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