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Intoxicating Hemp Swindle

Project CBD

The studys findings indicate that many so-called hemp products are infused with synthetic psychoactive cannabinoids, which can actually make users feel loopier than natural Delta-9 THC. Californias Assembly Bill 45, passed in 2021, explicitly states: Industrial hemp does not include cannabinoids produced through chemical synthesis.

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CDC Seeks Public Comments Regarding Chronic Pain Management

NORML

percent in 2016).” Additional clinical trial data indicates that cannabinoids possess synergistic activity with opioids, which “may allow for opioid treatment at lower doses with fewer [patient] side effects.”

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The Cannabis Cancer Connection

Project CBD

There is a growing body of anecdotal and scientific evidence that the “major cannabinoids” tetrahydrocannabinol (THC) and cannabidiol (CBD), certain “minor cannabinoids” (some without a name), and other cannabis compounds have antineoplastic action against cancer cells. THC binds to two types of cannabinoid receptors, CB1 and CB2.

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Quick Hits

Project CBD

Cannabinoid crystals. Across political boundaries, a group of scientists from Russia, China, and the USA crystallized the CB2 cannabinoid receptor. Many of these scientists were also involved in crystallizing the other main cannabinoid receptor, CB1 , in 2016.

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CBD Enhances Glucose Metabolism via Nuclear Receptors

Project CBD

Cannabinoid receptors CB1 and CB2 are the definitive and best-known targets of endogenous and plant-derived cannabinoids, but they’re far from the only ones. Two recent papers reiterate the point that to really understand cannabinoids (especially CBD) and the ECS, it’s essential to get to know the PPARs. doi:10.1111/bph.13497

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NORML Says DEA’s Newly Proposed Bulk Cultivation Rules Are “Unduly Onerous, Expensive, and Impractical”

NORML

In 2016, the DEA publicly announced that it would, for the first time, begin accepting applications from private entities wishing to grow research-grade cannabis. percent THC), or who wish to extract cannabinoids from plants that meet the federal definition of hemp, are not subject to the DEA’s licensing requirements.

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Gut Feeling

Project CBD

The endocannabinoid system is widely distributed throughout the gastrointestinal system, including not only CB1 and CB2 cannabinoid receptors but also other cannabinoid targets like PPARs, GPR55, and TRPV1. Even small doses of cannabis can soothe the stomach and stimulate the appetite.