The Joint Blog

NOVEMBER 8, 2020

The study concludes by stating that “To our knowledge, this is the first randomized controlled trial to demonstrate the benefit of cannabis oil – a THC-rich whole plant extract – on symptoms and on [the] quality of life of people with fibromyalgia. Pain attacks were also reduced.”. mg/mL of THC and 0.51

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Clinical Trials Oil Therapy Marijuana 49

The Cannigma

OCTOBER 27, 2021

The study compared herculean doses of delta-8 THC to delta-9 THC, and a crude marijuana extract (CME), which is something similar to RSO. 3150 mg/kg of delta-9 THC or delta-8 THC or were given 5,000 mg/kg of crude marijuana extract (CME). to 2000 mg/kg of THC or 5000 mg/kg of crude marihuana extract (CME).

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THC Research and Development Clinical Trials Cannabinoids 144

Cannabis Law Report

OCTOBER 15, 2021

In a notice scheduled to be published in the Federal Register on Monday, the agency said there’s been a “significant increase in the use of schedule I hallucinogenic controlled substances for research and clinical trial purposes,” and it wants authorized manufacturers to meet that growing demand.

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DEA Clinical Trials Extraction Marijuana 96

Cannabis Law Report

AUGUST 9, 2021

Investors will continue to keep an eye on several ongoing clinical trials, as well as private companies that are gearing up to go public over the coming quarters. The PsyIndex extended its move lower over the past week, even as two companies moved to senior stock exchanges. Market Performance. Weekly Performance: $128.84 (-2.22%).

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Clinical Trials Decriminalization Research and Development Treatment 105

The Cannigma

MARCH 7, 2022

Therefore, it makes sense that CBN is most commonly found in aged or improperly stored cannabis, and hardly ever present in fresh flower or low-temp extractions. What can the current clinical trials tell us? THC and is extracted from hemp, it’s generally considered legal. Converting THC to CBN happens through oxidation.

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THC Sleep Clinical Trials Cannabinoids 139

Cannabis Law Report

JUNE 7, 2021

Filament Health partnered with TrPR Psychedelic Research Program at UCSF to advance drug candidates through clinical trials. a federally-authorized psilocybin and cannabis research laboratory focused on extraction, analytical testing, and chemical process development. View All Index Constituents. Press Release. Press Release.

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Research and Development Clinical Trials Extraction Retail 98

Project CBD

AUGUST 6, 2019

Harvard University scientist Staci Gruber shared encouraging results from “the first open-label to double-blind clinical trial” assessing the impact of a high- CBD , low- THC sublingual tincture in patients who experience moderate anxiety. None of the participants had been using any cannabinoid-based products prior to this study.

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CBD Blood Pressure Research and Development Cannabinoids 222

Project CBD

OCTOBER 26, 2023

They conducted a double-blind, placebo-controlled phase 2 clinical trial using Sativex® in conjunction with temozolomide to treat recurrent glioblastoma multiforme (GBM). As part of the approval process for all markets, they have conducted critical Phase 2 studies on various conditions, including cancer.

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Research and Development Cannabinoids Terpenes Pharmaceutical 347

MedicalJane

MAY 21, 2020

The UNM researchers set out to examine the effectiveness of consuming “legal” hemp oil extracted from the whole Cannabis plant. This allowed the researchers to examine how “full-spectrum” whole plant extracted hemp oil influences brief episodes of pain sensitivity to an affected region. Westlund, Department of Anesthesiology.

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Oil Hemp Extraction Clinical Trials 100

Cannabis Law Report

JULY 12, 2019

Recent studies on the effectiveness of cannabidiol in the rare seizure disorders Dravet Syndrome and Lennox-Gastaut syndrome have prompted a biopharmaceutical company to perform clinical trials of its own to bring a cannabidiol based drug to the American market through the process of FDA approval.

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Extraction Pharmaceutical CBD Epilepsy 73

Cannabis Law Report

SEPTEMBER 14, 2021

Join Us in Advancing Cannabis Science to Elevate the Industry , by Pelin Thorogood, Co-founder and Executive Chair of Radicle Science, and Nicole Brown, Chief Innovation Officer of Open Book Extracts. About Open Book Extracts. About Radicle Science. Headquartered in Roxboro, N.C.,

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Extraction Research and Development Clinical Trials CBD 52

MedicalJane

OCTOBER 3, 2019

The United States Department of Defense and GW Pharmaceuticals are collaborating on a new clinical trial at the Montefiore Medical Center in New York. Eric Hollander, the Director of the Autism and Obsessive Compulsive Spectrum Program and Anxiety and Depression Program at Montefiore Hospital, is leading the clinical trial.

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Clinical Trials Epilepsy Pharmaceutical Treatment 74

The Cannigma

DECEMBER 14, 2021

The importance of this finding is that, similar to CBN, HHC may occur naturally as a degradation product in aged cannabis, extracts, and concentrates. Since HHC is extracted from hemp, it is federally legal and available to use in vapes and edibles (Shutterstock). Hexahydrocannabinol (HHC). Where is HHC available?

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Research and Development Clinical Trials Cannabinoids THC 116

Canna Care Docs

OCTOBER 3, 2023

One study supporting the efficacy of cannabinoids is in the Journal of Pain and Symptom Management, titled, “Multicenter, Double-Blind, Randomized, Parallel-Group Study of the Efficacy, Safety, and Tolerability of THC:CBD Extract in Patients with Intractable Cancer-Related Pain.”

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Chronic Pain Clinical Trials Patients Cannabinoids 105

Project CBD

AUGUST 6, 2019

Harvard University scientist Staci Gruber shared encouraging results from “the first open-label to double-blind clinical trial” assessing the impact of a high- CBD , low- THC sublingual tincture in patients who experience moderate anxiety. None of the participants had been using any cannabinoid-based products prior to this study.

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CBD Blood Pressure Research and Development Cannabinoids 179

Project CBD

MAY 3, 2023

Dr. Goldstein: We don’t have clinical trials to say, yes this is definitively beneficial or detrimental for children. But we may be on the cusp of having those trials, which would be very exciting. CannMed: I’m glad you brought up ADHD. Full disclosure: my son has been diagnosed with ADHD.

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Cannabinoids Sleep Clinical Trials CBD 213

Veriheal

MARCH 2, 2024

The revised legislation would permit clinical use and production of cannabis for medical CBD products, like Epidiolex , that have been approved in the U.S. and Europe to treat severe epilepsy, as well as other medical conditions.

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Legalization Epilepsy Clinical Trials THC 110

Miss Marijuana

JUNE 30, 2019

dietary supplement) Hemp Oil Extract product on various markers of physical and mental stress resilience, and perceived recovery from normal daily physical and mental stress.”. The Center for Applied Health Sciences’s (CAHS) main goal for this study: . RELATED: I’m A Business Owner Who Uses Cannabis & CBD For Anxiety.

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Sleep CBD Clinical Trials Oil 72

Cannabis Law Report

MARCH 18, 2020

The company, a leader in hemp-derived CBD extract products, has created an internal research and development division led by a former healthcare executive to focus on the science of hemp-derived phytocannabinoids, terpenes and flavonoid compounds. Charlotte’s Web Holdings, Inc. CW Labs and have an additional office in Boulder, Colo.

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Clinical Trials Research and Development Terpenes Hemp 59

Cannabis Law Report

JUNE 19, 2022

For example, compounds such as psilocybin, mescaline, ibogaine, and LSD are being evaluated in clinical trials, but the compounds themselves are unpatentable because their existence is well documented in the prior art. However, that does not mean that the path to patents is closed off.

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Clinical Trials Microdosing Data Pharmaceutical 52

The Cannigma

JUNE 23, 2022

More preclinical research involving cell cultures and animal models are needed, even before human clinical trials can take place to confirm the effects of cannabinoid acids on COVID infection. Meaning, it’s possible that the amount of CBDA and CBGA needed to prevent infection is unattainable in human doses. Where can you buy CBGA?

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Cannabinoids Research and Development Clinical Trials Extraction 113

The Cannigma

DECEMBER 12, 2022

In 1983, Ken Nelson was likely the first person to extract and smoke Sonoran Desert Toad (aka the Colorado River toad, Incilius alvarius ) venom. Clinical research: Research is focusing on 5-MeO-DMT use in depression and anxiety. Bufo is extracted by milking the venom from the toad’s parotoid glands.

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History Microdosing Research and Development Clinical Trials 119

Cannabis Law Report

FEBRUARY 1, 2022

Bod Australia has announced its planned phase IIB clinical trial of a cannabis extract with insomnia patients has received ethics approval. The trial will investigate the efficacy of a new prospective Schedule 3 CBD (cannabidiol) formulation on insomnia symptoms.

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Clinical Trials CBD Medicine Extraction 59

Cannabis Law Report

AUGUST 6, 2021

Clinical trials have shown that small doses of CBD help people to manage their social anxiety. When you’re buying CBD to treat your seizures, you need to make sure that you buy pure CBD extract. CBD is believed to stimulate the production of serotonin, your brain’s feel-good chemical. It’s Good for Your Brain.

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CBD Wellness and Beauty Treatment Pharmaceutical 105

The Joint Blog

JANUARY 31, 2021

According to a new study published in the Journal of Medical Case Reports , the daily use of high-CBD (cannabidiol) marijuana extracts is associated with improvements in the behavioral symptoms related to autism spectrum disorder (ASD). The individual was given very low-doses of marijuana extracts, no larger than 0.2 ml twice daily.

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Epilepsy Extraction Research and Development Clinical Trials 62

Veriheal

NOVEMBER 17, 2020

He ran clinical trials for big pharma’s GW Pharmaceuticals research division on Epidiolex. The study is titled, “Effects of CBD-Enriched Cannabis sativa Extract on Autism Spectrum Disorder Symptoms: An Observational Study of 18 Participants Undergoing Compassionate Use” and is published on the NCBI.

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Conditions Research and Development Pharmaceutical Clinical Trials 98

The Cannigma

MAY 6, 2021

It’s often suggested that delta-8-THC is a naturally occurring compound that can be extracted from hemp, but in fact, it only appears in very small amounts in nature. patent on a method for extracting delta-8 and no shortage of YouTube tutorials demonstrating the process, it’s not necessarily a good idea to consume such products.

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THC Cannabinoids Concentrates Hemp 145

The Cannigma

MAY 13, 2022

There have been a number of preclinical and clinical trials studying cannabis’ effects on pain. Made from oil extracted from camphor trees, camphor oil is a common ingredient in topical pain relief products. 12 Pinene had the ability to meditate chemical responses to inflammation in rodent trials.

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Terpenes Strains Chronic Pain Clinical Trials 111

Cannabis Law Report

DECEMBER 23, 2021

The story of GW Pharmaceuticals, the producers of Epidiolex, is instructive regarding the challenges and opportunities of operating in the pharmaceutical cannabis space; taking over 20 years to generate considerable sales and facing several setbacks in clinical trials. The current medical cannabis market is bursting with innovation.

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Pharmaceutical Clinical Trials Research and Development Cannabinoids 74

The Cannigma

JUNE 15, 2021

Another factor that increased CBD’s popularity was the FDA approval of an antiepileptic cannabis-based drug named Epidiolex — a highly concentrated CBD extraction mixed with sesame oil and some flavoring. In addition, hemp-derived extracts and other products tend to have less diverse terpenoid and cannabinoid profiles. Shutterstock).

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CBD Research and Development Epilepsy Extraction 122

MMJ Recs

JULY 9, 2024

Methods of Consumption Medical marijuana can be consumed in various forms, including smoking or vaporizing dried flowers, consuming edibles or beverages infused with cannabis extracts, or using oils and tinctures that are applied sublingually or added to food.

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Marijuana Treatment Cannabinoids Patients 111

Cannabis Law Report

JUNE 30, 2021

In addition, the company aims to predict what treatments are most effective in addressing these conditions, including psychedelics, which have shown tremendous promise in early clinical trials. Mental Health Challenges. Psychedelics could offer a better alternative for many patients. Psychedelics Provide a Solution. Looking Ahead.

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Treatment Clinical Trials Research and Development Data 52

LifeCannMD

AUGUST 2, 2024

More clinical trials are needed to establish definitive efficacy and safety profiles. – Details: The research emphasized the need for controlled clinical trials to better understand the optimal dosages and strains. The study also noted that patients using medical cannabis had improved quality of life.

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Clinical Trials Marijuana Research and Development Cannabinoids 52

Otherside Farms

JANUARY 14, 2019

This has pushed into oblivion the positive impact of marijuana seeds and its extracts on various body systems, including the cardiovascular system, the brain and the reproductive system. Marijuana has been used for centuries for medicinal purposes; however, it has earned a bad name due to its widespread abuse as an addictive substance.

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SpeedWeed

MARCH 28, 2021

CANNABIS CULTURE – The results are now in after the first-ever legal clinical trial into the use of cannabis to treat PTSD, but did the DEA’s rules taint the outcome? It was also unique because it used whole-plant cannabis, rather than single-molecule extracts or synthetic pharmaceutical cannabinoids. .

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Clinical Trials DEA Treatment THC 52

The Cannigma

MARCH 15, 2021

The Syqe inhaler was developed in Israel through several clinical trials , which found that measured, uniform doses can be a safe and efficient way to treat chronic pain. If it wasn’t obvious, the Syqe inhaler isn’t the sort of device you’ll find at your head shop next to the dab rigs and Polar Bear Snuff. Is it a bong? sorta both?

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Concentrates Clinical Trials Chronic Pain Pets 143

SpeedWeed

JULY 23, 2021

“We’re interested in how cannabinoids affect the nervous system, the brain, and in particular, we’re very interested in Alzheimer’s disease,” said Dr. Tyrell Towle, director of chemistry and extraction at MedPharm. Denver Company Moves Forward with Research License . Denver Company Moves Forward with Research License .

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Clinical Trials Research and Development DEA Cannabinoids 52