The Cannigma

JUNE 20, 2021

One clinical trial published in 2015 found “significantly higher blood THC” values among test subjects who consumed alcohol with cannabis, which they said could “possibly explain increased performance impairment observed from cannabis-alcohol combinations.” The same terpenes are present in fresh herbs like basil as well as in cannabis.

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MedicalJane

MAY 21, 2020

Animal studies are not only valuable, they can also be superior to clinical trials in some cases because they can circumvent human biases and expectancy effects, or perceptual and cognitive reactions to participation in cannabis-based experiments. Hemp” is defined in the Act as “the plant Cannabis sativa L.

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Project CBD

MAY 3, 2023

Dr. Goldstein: We don’t have clinical trials to say, yes this is definitively beneficial or detrimental for children. But we may be on the cusp of having those trials, which would be very exciting. CannMed: I’m glad you brought up ADHD. Full disclosure: my son has been diagnosed with ADHD.

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Cannabis Law Report

MARCH 18, 2020

The company, a leader in hemp-derived CBD extract products, has created an internal research and development division led by a former healthcare executive to focus on the science of hemp-derived phytocannabinoids, terpenes and flavonoid compounds. Charlotte’s Web Holdings, Inc. CW Labs and have an additional office in Boulder, Colo.

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Clinical Trials Research and Development Terpenes Hemp 59

CannaMD

SEPTEMBER 28, 2020

For example, high-CBD strains are also high in myrcene , a sedating terpene compound. Scientists have also studied combinations of THC and CBD, such as Sativex clinical trials that show patients’ marked improvement in sleep. Research is complex because there are compounding factors.

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Veriheal

APRIL 11, 2022

In particular, of all the components contained in the cannabis plant— including cannabinoids , terpenes , and flavonoids — the cannabis compound tetrahydrocannabinol (THC) has proven to harbor medicinal benefits when used in specific formulations. The debate surrounding cannabis’ potentially therapeutic powers has ensued for decades.

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Miss Marijuana

MAY 13, 2020

A Certificate of Analysis (COA) shows the product was made properly, does not contain pesticides or heavy metals (and verifies CBD content as well as other compounds, such as terpenes). Full spectrum means that the product contains most of the naturally occurring cannabinoids and terpenes of the plant. So which one works best?

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CBD Blood Pressure Clinical Trials Tincture 98

The Cannigma

JULY 1, 2022

Because of this variability in the plant, and because of a lack of standard methods–like chemical analyses of cannabinoids or terpenes–has led to inconsistent scientific results. This is because these types of studies control the most variables to ensure that the results that come out of the trial are as reliable as possible.

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Puff Puff Post

JANUARY 13, 2020

Generally speaking, 99 cent stores sell CBD that doesn’t have its terpenes or other cannabinoids measured. Terpenes are the chemicals that give cannabis varieties their unique flavor or scent. Terpenes interact with both cannabidiol and THC and change the effects that either drug has on the body. Physicians at Mt.

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CBD Clinical Trials Research and Development Oil 52

Puff Puff Post

JANUARY 13, 2020

Generally speaking, 99 cent stores sell CBD that doesn’t have its terpenes or other cannabinoids measured. Terpenes are the chemicals that give cannabis varieties their unique flavor or scent. Terpenes interact with both cannabidiol and THC and change the effects that either drug has on the body. Physicians at Mt.

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Project CBD

NOVEMBER 11, 2023

We rate levels of evidence, and a high level may be a controlled randomized clinical trial (RCT), but there are also observational studies. And then it’s not just the cannabinoids, there are terpenes and essential oils and other things, all of which may contribute to the effects. Which cannabinoids do you standardize for?

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Sensi Seeds

NOVEMBER 23, 2018

However, recent research on the cannabinoid and terpene profiles of different cannabis varieties mean we need to reassess what we thought we know about indicas and sativas being defined by their THC:CBD ratio. And yet others swear by hybrids, for the best of both worlds. What type of cannabis will make you laugh?

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The Joint Blog

FEBRUARY 18, 2020

” Clinical trial data published in 2017 in in the journal European Neuropsychopharmacology previously reported that the administration of whole-plant cannabis extracts is associated with improvements in cognition and behavior in subjects with ADHD. 9-tetrahydrocannabinol (THC).

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The Joint Blog

JANUARY 23, 2020

” The systematic review of the literature “was conducted during 2019, assessing the data from all case studies and clinical trials involving medicinal cannabis or plant-derived isolates for all major psychiatric disorders (neurological conditions and pain were omitted).”

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Freedom Leaf

JANUARY 10, 2018

“We’re actively working toward developing new genetics to work on efficacy and assist the patients in Israel still operating with our nurse-run clinics in order to better provide the right dosage and strains for the patients who are referred to us by the Ministry of Health,” Stephen Gardner, Tikun Olam’s chief marketing officer, tells Freedom Leaf.

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MMJ Recs

JULY 19, 2024

Clinical Research Findings: What Studies Say About Cannabis and Anxiety Numerous studies have explored cannabis’s efficacy in alleviating anxiety symptoms. However, more rigorous clinical trials are needed to establish definitive conclusions. Image by Margo Amala on Unsplash.

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The Cannigma

JUNE 24, 2021

While more human clinical trials are needed, the current evidence suggests there may be potential therapeutic benefits for the following ailments: Chronic pain — the most common reason people turn to medical cannabis in the United States today. But when taken together, these chemicals are thought to work greater in concert.

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CannaTech

SEPTEMBER 16, 2018

Over time extended clinical trials will continue to map out the plant’s therapeutic effects, supporting it as an alternative medicine offering relief for a long list of conditions. There simply isn’t enough research on cannabis to support its efficacy, especially in comparison to traditional medicine like opioids.

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MMJ Recs

JULY 11, 2024

Researchers are exploring targeted formulations that combine different ratios of cannabinoids and terpenes to optimize sleep outcomes. However, more robust clinical trials are needed to validate these findings and determine the optimal dosages and treatment regimens for each disorder.

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CannaMD

AUGUST 8, 2020

Prior to receiving FDA approval, Epidiolex underwent a number of clinical trials establishing the medical efficacy of CBD. Hemp oil also lacks critical terpenes and other secondary cannabinoids found in cannabis oil. According to Project CBD : A huge amount of industrial hemp is required to extract a small amount of CBD.

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MMJ Recs

DECEMBER 28, 2023

Medical marijuana, especially strains with high levels of the terpene myrcene and sedating indica varieties, has shown promise in promoting sleep. Cannabis for Insomnia: Understanding Its Sleep-Inducing Properties Insomnia is a common sleep disorder that can significantly impact daily functioning and overall well-being.

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TheAnswerPage

JANUARY 11, 2022

the components of the cannabis plant (phytocannabinoids, terpenes, and flavonoids) and the health effects of cannabinoid-based therapy in the various patient populations. Results of an observational study merely suggest an association between a therapeutic agent or an event and an outcome.

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Miss Marijuana

MAY 13, 2020

A Certificate of Analysis (COA) shows the product was made properly, does not contain pesticides or heavy metals (and verifies CBD content as well as other compounds, such as terpenes). Full spectrum means that the product contains most of the naturally occurring cannabinoids and terpenes of the plant. So which one works best?

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CBD Blood Pressure Clinical Trials Tincture 52

The Cannigma

JUNE 15, 2021

This means that all cannabinoids (including trace amounts of THC), terpenes, flavonoids, and other phytonutrients present in the plant are preserved and used in the final product. With the exception of THC, all cannabinoids, terpenes, flavonoids, and other phytonutrients are preserved and used in the final product.

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CBD Research and Development Epilepsy Extraction 122

MMJ Recs

JULY 5, 2024

Understanding THC Chemical Structure THC’s chemical structure consists of a cyclic ring connected to a hydrocarbon chain, making it a terpene phenolic compound. Numerous clinical trials are underway to further investigate THC’s efficacy, safety, and potential interactions with other medications as well.

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Miss Marijuana

MARCH 15, 2021

The rich smell provided by the pinene and myrcene terpenes make this flower a breath of fresh air for those looking for a strain with earthy tones for the nostrils. Many people tout this strain’s powerful effect on their lives, and it will be curious to see what the medical community does once clinical trials are initiated.

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The Cannigma

DECEMBER 22, 2021

I do want to say that when it comes to anxiety, sleep, I mean, what we do, for example, in Bazelet, which is quite unique, as far as oil products are concerned, this is something that is we have a lot of intellectual property on the use of terpenes in creating cannabis formulations. We have, I think, eight PhDs.

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SpeedWeed

AUGUST 4, 2021

We will be investing heavily in research and development and clinical trials to develop a full range of medicines, ready for registration and marketing authorization in Australia and Europe. . Our initial product line will include a range of high THC flower, oils, tablets, and terpenes. View original article.

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Cannabis Law Report

NOVEMBER 7, 2019

With a strong focus on research and development ranging from agronomic research through to clinical trials Cannatrek has an extensive R&D portfolio from Seed to Patient. Cannatrek is actively working on clinical trial protocols with a dedicated focus on mental health.

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MMJ Recs

AUGUST 1, 2024

Popular Strains for HIV/AIDS Patients Certain cannabis strains are particularly beneficial for HIV/AIDS patients due to their specific cannabinoid and terpene profiles. With hope, increased clinical trials and studies will provide robust evidence, guiding healthcare providers in formulating fruitful treatment plans.

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The Cannigma

MAY 13, 2022

There have been a number of preclinical and clinical trials studying cannabis’ effects on pain. The best type of cannabis for dealing with chronic pain tends to be type I or type II strain with a terpene profile that includes linalool, pinene, beta-caryophyllene, limonene, or myrcene. Can topical terpenes alone help with pain?

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Terpenes Strains Chronic Pain Clinical Trials 111

The Cannigma

JANUARY 13, 2023

Based on the limited existing evidence, the best cannabis strain for migraines may be a Type II that includes both THC and CBD, and a terpene profile that includes beta-caryophyllene, myrcene, linalool, limonene, bisabolol, humulene or pinene. The study called out pinene, myrcene, and beta-caryophyllene as specifically useful terpenes.

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Project CBD

OCTOBER 26, 2023

They conducted a double-blind, placebo-controlled phase 2 clinical trial using Sativex® in conjunction with temozolomide to treat recurrent glioblastoma multiforme (GBM). See chapter: Cannabinoids, Terpenes & Flavonoids ). 21,22 ( See chapter: Cannabinoids, Terpenes & Flavonoids ).

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Veriheal

SEPTEMBER 6, 2022

Recent research has found that terpene and cannabinoid profiles are far more significant when trying to produce specific effects. Terpene and cannabinoid profiles of the cannabis you are consuming will also impact the effects experienced. Indica has a reputation for making people feel calm and mellow and helping to induce sleep.

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Cannabis Law Report

NOVEMBER 24, 2021

Research into the plant’s chemical compounds has also revealed a rich array of terpenes and flavonoids that may also account for the plant’s therapeutic effects (Kotsirilos and McGregor 2021 ). It is unclear whether doctors are feeling completely reassured by laboratory and clinical trial research into medicinal cannabis.

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The Cannigma

FEBRUARY 11, 2021

Listen & Subscribe: When Mara Gordon started using medical cannabis there wasn’t any lab testing — or any way to know how much of each cannabinoid or terpene was in a given strain. You know, started doing clinical trials through Zelda Therapeutics, and all the other things I’ve done. So I just started doing it myself.

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Canna Care Docs

JUNE 22, 2018

THC is simply one cannabinoid present within cannabis that interacts with many other cannabinoids present within the plant, including aromatic terpenes which all contribute to what is known as the entourage effect.

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