Project CBD

FEBRUARY 27, 2023

Researchers have been investigating the use of cannabis to treat fibromyalgia’s constellation of symptoms for decades, with early clinical trials in the 2000s 1-4 suggesting a possible benefit of both pure THC and flower in managing the disease. It’s not a new idea. That seemed to make all the difference. 22,7 (2006): 1269-76.

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THC CBD Clinical Trials Sleep 144

The Cannigma

OCTOBER 27, 2021

The good news first – if you were for whatever reason to give a rhesus monkey a “massive” dose of THC it probably won’t die, though it may become extremely stoned and sit for hours with its head in its hands. Massive doses of THC will kill rats – lots of rats. Hypothermia is a known effect of THC, even in humans.

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THC Research and Development Clinical Trials Cannabinoids 144

NORML

DECEMBER 6, 2019

Authors concluded, “Further research is needed in this field, but CBD, as an alternative to THC, should be taken into consideration in the therapy of masticatory muscles in patients with TMD.” Subjects receiving treatment reported no adverse effects.

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Clinical Trials Patients CBD Therapy 108

The Cannigma

MARCH 7, 2022

So much attention is placed upon THC and CBD that sometimes the less abundant cannabinoids are forgotten about or not appreciated fully. Long before THC was discovered in the 1940s , CBN was first identified at the turn of the 20th century from a plant that was then known as Indian hemp. Converting THC to CBN happens through oxidation.

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THC Sleep Clinical Trials Cannabinoids 139

Puff Puff Post

MARCH 10, 2020

InMed and CHDR are currently preparing the Clinical Trial Application for a second Phase 1 clinical trial (755-102-HV), planned to begin in the second quarter of 2020, which will examine the local safety of INM-755 on small areas of wounded skin in healthy volunteers.

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Clinical Trials Pharmaceutical Research and Development Cannabinoids 84

NORML

APRIL 15, 2019

.” A separate study published in 2017 reported that U-Miss samples contain far lower levels of both THC and CBD than do commercially available cannabis. Clinicians wishing to conduct FDA-approved clinical trials on cannabis have long complained that federally-provided samples are of inferior quality.

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Hemp Clinical Trials Marijuana Programs 197

Project CBD

OCTOBER 26, 2023

There is a growing body of anecdotal and scientific evidence that the “major cannabinoids” tetrahydrocannabinol (THC) and cannabidiol (CBD), certain “minor cannabinoids” (some without a name), and other cannabis compounds have antineoplastic action against cancer cells. THC binds to two types of cannabinoid receptors, CB1 and CB2.

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Research and Development Cannabinoids Terpenes Pharmaceutical 347

The Cannigma

MAY 6, 2021

Delta-8-THC, a close relative of the more famous delta-9-THC, acts in many of the same ways producing a similar high and even some of the same therapeutic effects. What is delta-8-THC. Along with delta-9-THC, delta-8 is one of the few cannabinoids considered to be intoxicating. (El Sound too good to be true?

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FloridaMarijuana.net

AUGUST 16, 2018

The clinical trials for medications take years and to this date, there have been no effective medications to properly treat and/or cure Dementia. The Journal of Psychopharmacology analyzed a study in which THC was used to determine its effects on Dementia patients’ balance. 9-tetrahydrocannabinol (?9-THC)

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Clinical Trials Marijuana Patients Pharmaceutical 184

Veriheal

JANUARY 28, 2022

Contributing to Israel’s list of impressive discoveries is a new study, published in Translational Psychiatry , showing that tetrahydrocannabinol (THC) -rich cannabis oil can be effective in treating the symptoms of autism spectrum disorder (ASD). However, THC is more widely available. Is Cannabis Oil Safe for Children?

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Oil THC Research and Development Treatment 104

The Cannigma

FEBRUARY 1, 2023

To date, very few human clinical trials have been conducted to assess the effectiveness of THC or CBD in treating cancer. When THC binds to the CB1 receptor, this is what produces the well-known high associated with cannabis. Importantly, research is underway to determine the antitumor effects of cannabinoids!

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Clinical Trials Research and Development Therapy Cannabinoids 145

FloridaMarijuana.net

JUNE 13, 2018

In 1975, The Journal of the National Cancer Institute published a revolutionary study within the medical industry which showed that tumor growth slowed or stopped in laboratory mice after the use of THC and cannabis compounds. Another variety Rick Simpson Oil (RSO) was designed by a cancer patient and has more of a THC concentration.

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Clinical Trials Marijuana Patients Chronic Pain 189

The Cannigma

OCTOBER 11, 2021

No clinical trial was used in the compilation of the study. The researchers themselves wrote that the study is the first “to document self-reported efficacy of CBG-predominant products,” and provides further indication that “CBG-predominant cannabis-based medicines should be studied in randomized controlled trials.”.

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Conditions Clinical Trials Chronic Pain Cannabinoids 132

CannaMD

MARCH 8, 2021

House Bill 1455, which seeks to “cap” THC potency, limit physician prescribing practices, and all but eliminate physician and dispensary advertising, has come under sharp criticism from patients, physicians, and industry insiders alike. Studies Supporting THC. Food & Drug Association’s role in H.B. Florida H.B.

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THC Research and Development Treatment Patients 116

SpeedWeed

FEBRUARY 18, 2021

The trial , titled “Cannabis is associated with clinical but not endoscopic remission in ulcerative colitis: A randomized controlled trial,” was published in the PLoS One journal and outlines the effects of high-THC cannabis use on ulcerative colitis. THC and Inflammation. View original article.

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Clinical Trials Treatment Data THC 52

Veriheal

JANUARY 11, 2023

Not only this, but Gaize recently completed the largest clinical trial into cannabis impairment , and the results are set to transform the realm of workplace and road safety. How do you feel about this being the largest cannabis impairment clinical trial ever?

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Clinical Trials THC Data Safety 98

FloridaMarijuana.net

AUGUST 9, 2018

In the lab, Sarne and his team “injected mice with a single, low dose of THC either before or after exposing them to brain trauma. A control group of mice sustained brain injury, but did not receive the THC treatment. Relieve pain, inflammation and nausea. Relieve symptoms related to neurological disorders.

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Marijuana Patients Clinical Trials Treatment 190

The Joint Blog

NOVEMBER 8, 2020

For the study researchers examined the efficacy of high-THC marijuana oil versus a placebo in patients with fibromyalgia over an eight-week period. mg of THC and 0.08 It can be found below: Objective: To determine the benefit of a tetrahydrocannabinol (THC)-rich cannabis oil on symptoms and quality of life of fibromyalgia patients.

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Clinical Trials Oil Therapy Marijuana 49

Otherside Farms

JANUARY 24, 2019

Geoffrey Guy, chairman of the pharmaceutical company, told reporters that the purified drug contains no tetrahydrocannabinol (THC), the psychotropic ingredient in marijuana causing the recreational high. Source: FDA Approves Marijuana-Based Epilepsy Drug For Use On Kids In Clinical Trials. In the upcoming U.S.

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Clinical Trials Epilepsy Marijuana Pharmaceutical 45

Medical Marijuana Program Connection

APRIL 4, 2023

Diabetic patients administered a sublingual spray containing CBD and THC show improvements in their blood sugar and cholesterol levels, according. Read More

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Clinical Trials THC CBD Patients 52

Veriheal

AUGUST 22, 2022

Clinical trials into cannabis’ potential as an opioid replacement are well underway in South Africa. Quite frankly, the clinical trials couldn’t have come at a better time. The flower contained high levels of THC in the range of 15-25 milligrams, with CBD content resting on the lower end of the spectrum at 0.5

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Clinical Trials Chronic Pain Hydroponic Strains 116

Cannabis Law Report

DECEMBER 2, 2021

(IGC) is excited to present preliminary positive secondary end point findings from its Phase 1 clinical trial for IGC-AD1. The investigational new drug, IGC-AD1, is IGC’s proprietary Tetrahydrocannabinol (THC)-based candidate designed to treat certain symptoms of Alzheimer’s disease.

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Clinical Trials Data Patients THC 40

LifeCannMD

JULY 3, 2024

Medical marijuana contains numerous compounds, but the two most studied are: THC (tetrahydrocannabinol): The psychoactive component responsible for the “high” associated with marijuana. THC, at low doses, can produce a calming effect, but higher doses may increase anxiety in some individuals.

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Treatment Clinical Trials Marijuana Sleep 96

Project CBD

AUGUST 6, 2019

Harvard University scientist Staci Gruber shared encouraging results from “the first open-label to double-blind clinical trial” assessing the impact of a high- CBD , low- THC sublingual tincture in patients who experience moderate anxiety. Twenty percent of the samples contained less CBD than indicated on the label.

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CBD Blood Pressure Research and Development Cannabinoids 222

Cannabis Law Report

DECEMBER 14, 2021

IGC” or the “Company”) today announced positive primary endpoint data for its Phase 1 clinical trial for IGC-AD1, which is a proprietary cannabinoid-based investigational new drug candidate for patients who have Alzheimer’s disease. The primary endpoint of our Phase 1 clinical trial was to test and demonstrate safety and tolerability.

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Clinical Trials Safety Data Patients 40

Leafly

OCTOBER 4, 2022

A drug that blocks the brain's cannabinoid receptors is now in clinical trials and showing promising results. The post Are you too high? A promising new ‘comedown drug’ may be on the way appeared first on Leafly.

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Clinical Trials Cannabinoids Medicine THC 105

The Fresh Toast

JULY 22, 2020

Clinical trial results indicate cannabis could provide an alternative or adjunctive treatment to sickle cell patients. Marijuana Shows Promise In Sickle Cell Disease Treatment. The post Marijuana Shows Promise In Sickle Cell Disease Treatment appeared first on The Fresh Toast.

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Treatment Clinical Trials Marijuana Patients 105

Cannabis Law Report

NOVEMBER 29, 2019

Tetrahydrocannabinol (THC) is the element in cannabis that gets a person high. THC is the psychoactive compound in cannabis. But, THC has a similar chemical makeup with cannabidiol or CBD. CBD combats THC’s effects. THC alters communication functions. That’s why some people choose THC oil. THC Oil Benefits.

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Oil THC Cannabinoids Research and Development 80

Project CBD

JANUARY 23, 2023

THC for Tumors? “With the increasing use of medical cannabis worldwide, this finding is of major clinical importance.” While plenty of preclinical evidence exists demonstrating the anti-cancer effects of cannabinoids, clinical trials investigating relationships between cannabis use and cancer outcomes in actual patients are rare.

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Clinical Trials Treatment Patients Cannabinoids 130

FloridaMarijuana.net

AUGUST 15, 2018

Additionally, the ACPA reported on a clinical trial that suggests that inhaled cannabis may provide short-term relief from Neuropathy. The compounds THC (tetrahydrocannabinol) and CBD (cannabidiol) found in cannabis signal the same cannabinoid receptors as anandamide. Mazanet for The Foundation for Peripheral Neuropathy.

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Chronic Pain Marijuana Patients Clinical Trials 150

The Cannigma

JUNE 14, 2021

‘Junk’ cannabis ‘ill-suited for clinical trials’. The cannabis grown at the University of Mississippi “is junk, ill-suited for clinical trials, and genetically closer to hemp than the marijuana available from dispensaries and used by Americans nationwide,” according to the lawsuit. A promise made years ago.

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DEA Research and Development Clinical Trials Pharmaceutical 133

Project CBD

MAY 3, 2023

Dr. Goldstein: It appears that CBG does a lot of things that THC does and a lot of things that CBD does — but maybe even a little bit better. It’s kind of a bridge between THC and CBD. CannMed: It’s interesting that you say CBG is a bridge between THC and CBD. CBG is not intoxicating or impairing.

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Cannabinoids Sleep Clinical Trials CBD 213

Project CBD

NOVEMBER 11, 2023

Some years ago, our government allowed the use of Marinol, which is synthetic THC, especially for cancer patients. We rate levels of evidence, and a high level may be a controlled randomized clinical trial (RCT), but there are also observational studies. I think it’s more useful when THC is also present.

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Medicine Research and Development Pharmaceutical Cannabis 306

Canna Care Docs

JUNE 22, 2018

An Introductory Lesson on THC Basics For Medical Cannabis Patients. But one of the most famous and most widely known phrases associated with the plant will always be THC, or more appropriately, delta-9-tetrahydrocannabinol. THC Basics: Perceptions in Today’s Society.

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THC Patients Blood Pressure Clinical Trials 66

Cannabis Law Report

JULY 4, 2021

The level of THC in CBD products should fall below 0.2% Also, alone it won’t create the “high” sensation associated with the use of Tetrahydrocannabinol or THC. Clinical trials across the EU have also shown CBD oils and other hemp products to have a potential range of benefits. What is THC? CBD vs THC.

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THC CBD Legalization Oil 81

Veriheal

MARCH 2, 2024

Yet, at the same time, the new amendment to Japan’s cannabis control legislation will also impose harsher bans and punishments for the consumption of recreational tetrahydrocannabinol (THC)-containing cannabis products. In Japan, THC-based products are designated as narcotics to be regulated.

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Legalization Epilepsy Clinical Trials THC 110

Project CBD

MARCH 21, 2023

That’s what appeared to happen in rats injected with the synthetic CB1 agonists WIN55,212‐2 and CP55,940 in a 2010 study 4 and THC and CBD in a 1:1 ratio in a 2011 follow-up study. Despite all this, there is a potential biological rationale for the treatment of tinnitus with cannabinoids, the authors explain.

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Cannabinoids Clinical Trials Sleep Blood Pressure 144